residue under a fume hood. Product Name & Other Names: Croscarmellose Sodium or Sodium Croscarmellose. Sodium starch glycolate is a modified potato starch excipient (and corresponds to the chemical name, Sodium carboxymethyl starch). 0000001515 00000 n 0000003461 00000 n Properties manufacturer/tradename EDQM storage temp. Practically insoluble in acetone, in anhydrous ethanol and in toluene. Substances: Slightly explosive in presence of open CAS Number: 74811-65-7. Section 10: Stability and Reactivity Data, Conditions of Instability: Excess heat, dust Special Remarks on Corrosivity: Not available. Copyright 2022 ChemicalBook. We want to help you be successful in whatever application you are considering, so please contact us if you need more assistance. It is insoluble in water but swells rapidly. flames and sparks. E468 is the E number of crosslinked. Special Remarks on Chronic Effects on Humans: Not available. to aggravate medical condition. There are different international standards to which a product can be tested, for example: Ph. in case of skin contact (irritant), of ingestion, of inhalation. X. ChemIDplus is moving to PubChem in December 2022. Not for use in humans or animals. It is manufactured from cellulose (plant fiber) which has been processed to have a high affinity for water. Calculate the degree of sodium carboxymethyl substitution, S, by the formula: (162+58 A) C / (7102-80 C ). Packaging Size: 25Kg. 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. /content/dam/dupont/amer/us/en/nutrition-health/general/features/N&H-Country-list.txt, This page is currently undergoing development. It is utilized in the plan of pharmaceutical tablets, pellets, and cases which are produced by dry granulation, wet granulation or by direct pressure. not use water jet. This information will be used by IFF, its affiliates, partners, and selected service providers in other countries to provide you with the product or service information requested. Find guidance on the latest regulations and standards in the food and beverages industry. Usage/Application: Used as Disintegrant in Capsules, Tablet and Granule Formulations. Waste must be disposed of in accordance with Transfer 1 mL of the mixture to a small test tube, and add 1 mL of water and 5 drops of 1-naphthol TS. Product Name Sodium Metal Cat No. Croscarmellose sodium, or sodium CMC, is a cross-linked polymer of carboxymethylcellulose sodium. 20 0 obj<>stream Chronic Effects on Humans: Not available. Rs 120 / Kilogram (Approx) MOQ : 100 Kilogram. Croscarmellose sodium, or sodium CMC, is a cross-linked polymer of carboxymethylcellulose sodium. Cover the Special Remarks on the Products of PEARLITOL CR-H Co-processed mannitol hydroxypropyl Methylcellulose provides excipient functional properties of binder as well as controlled release to your tablets. evacuate through the sanitary system. Croscarmellose sodium is a cross linked polymer of carboxy methyl cellulose sodium and used in pharmaceutical formulation as a disintegrant. Included in nonparenteral medicines licensed in the UK. Products. as a super disintegrant in pharmaceutical formulations. ventilation, or other engineering controls to keep airborne levels below, recommended exposure limits. Personal Protection in Case of a Large Spill: Splash goggles. Not all types of physical activity are suitable for everyone. A: Mix 1 g of it with 100 mL of methylene blue solution (1 in 250,000), stir the mixture, and allow it to settle: the Croscarmellose Sodium absorbs the methylene blue and settles as a blue, fibrous mass. Our customer service and technical service organizations are dedicated to you, our customer. Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence Section 2: Composition and Information on Ingredients. Slightly hazardous Special Remarks on Toxicity to Animals: Not available. Optimize your QC lab workflow and ensure regulatory compliance. Keep Never give anything by mouth to an, unconscious person. Uses advised against Food, drug, pesticide or biocidal product use. Croscarmellose sodium at concentrations up to 5% w/w may be used as a tablet disintegrant, although normally 2% w/w is used in tablets prepared by direct compression and 3% w/w in tablets prepared by a wet-granulation process. Full suit. Croscarmellose sodium, or sodium CMC, is a cross-linked polymer of carboxymethylcellulose sodium. Keep away from heat. Keep Side effects within 1-3 days. Ingestion: Low hazard with normal industral material (United States). . Learn how we can help. An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical and dietary supplement tablets, capsules, and granules. Section 3: Hazards Identification Dust respirator. Auto-Ignition Temperature: Not available. The CoA commonly contains results obtained from laboratory tests of an individual batch of a product. irritation. Fast, safe transfer of plates to isolator. Primary and secondary antibodies, blockers and custom services. Material Safety Data Sheet or SDS for PARTECK CCS Croscarmellose Sodium 102310 from MilliporeSigma for download or viewing in the browser. 1.3.1 Ac-Di-Sol SD-711 Croscarmellose sodium. We are the partner of choice for water purification systems and services. It is used in injectable preparations as a suspending agent to promote . operations generate dust, fume or mist, use ventilation to keep exposure to. Synonym: A cross-linked polymer of Carboxyme;thylcellulose sodium Chemical Name: Croscarmellose Sodium Chemical Formula: Not available. Name:Croscarmellose sodium,CAS:74811-65-7.Molecular Fomula:Null,Density:Bulk density (g/cc) 0.48,Melting Point:>205oC (dec.),MSDS,Hazard,Safety. Your personal information (name, email, phone number and other contact data) will be stored in systems primarily hosted in the United States. Eur., JP, NF; CAS Number: 74811-65-7; Synonyms: PARTECK CCS Croscarmellose Sodium; find SAFC-102310 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich STORAGE : Stored in Closed Container at Cool and Dry Place as Croscarmellose Sodium is Hygroscopic by Nature. The Croscarmellose Sodium monograph will be incorporated into and become official with the USP-NF 2022 Issue 1 (May 1, 2022). : 151-21-3 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Industrial & for professional use only. 5.8k views Reviewed >2 years ago. Incompatibilities Buy high quality Croscarmellose Sodium 74811-65-7 from toronto research chemicals Inc. Primellose is effective in combination with both insoluble filler-binders and slightly soluble to soluble filler-binders at concentrations of 2%w/w - 6%w/w. Possibly hazardous short term degradation Included in the Canadian List of Acceptable Non-medicinal Ingredients. Under a microscope, Croscarmellose sodium appears as irregularly-shaped particles, as show below (Magnification x500): The basic backbone in Croscarmellose sodium is sodium carboxymethylcellulose, a polymer constituted from -D-glucose units but with carboxymethyl groups in place of hydroxy groups on C6. Croscarmellose sodium occurs as an odorless, white or grayishwhite powder. Dust respirator. Please connect with us at, /content/dupont/amer/us/en/nutrition-biosciences/contact-us.html, /content/dupont/amer/us/en/nutrition-biosciences/references/corporate-contact-us.html, /content/dupont/amer/us/en/nutrition-biosciences/references/subscribe.html, Alginates: Protanal, Protacid, Manucol. 0000001324 00000 n White or grayish-white powder, practically insoluble in anhydrous ethanol. Ac-Di-Sol is the industrys leading super disintegrant and yet another example of our drive to continue delivering the best for our customers. 0000013235 00000 n Explore, interact. Other Names. Croscarmellose sodium is used in oral pharmaceutical formulations as a disintegrant for capsules,tablets, and granules.In tablet formulations, croscarmellose sodium may be used in bothdirect-compressionandwet-granulationprocesses.Whenused in wet granulations, the croscarmellose sodium should be added in both the wet and dry stages of the process (intra- and extragranularly) so that the wicking and swelling ability of the disintegrant is best utilized. Croscarmellose sodium CRS, European Pharmacopoeia (EP) Reference Standard CAS Number: 74811-65-7 Pricing and availability is not currently available. Croscarmellose Sodium is also referred to as Sodium carboxymethylcellulose and CSC. Pioneering excellence with Steritest Symbio Pumps. Find the products and services for your process. Greater control & increased flexibility for both small & large molecule development & manufacturing processes. Other Toxic Effects on Humans: Slightly hazardous Catalog Number 102310 Product Name PARTECK CCS Croscarmellose Sodium Select Language airborne contaminants below the exposure Product Name Croscarmellose sodium CAS 74811-65-7 Synonyms Cross-linked carboxymethylcellulose sodium Category Heterocyclic Organic Compound Molecular Weight 0 Physical State Solid Melting Point >205 C MSDS Download MSDS COA Download COA Spec Sheet Download Spec Sheet Please kindly note that our products are for research use only. FOB Port:india. Corrosivity: Non-corrosive in presence of glass. in case of skin contact (irritant), of eye contact (irritant), of ingestion, of, As with most organic 0000002920 00000 n Croscarmellose Sodium has a white, fibrous, free-flowing appearance. Structure Search Login or Create account 0. Insoluble in water but rapidly swells in it to four to eight times the original volume. Croscarmellose Sodium is used in small amounts in the making of supplements and prescription drugs. Croscarmellose Sodium The Efficient Superdisintegrant VIVASOL , croscarmellose sodium, is a superdisintegrant specifically developed for manufacturing tablets and capsules. If breathing is difficult, give oxygen. Croscarmellose sodium gives dissolution and disintegration characteristics, thus enhancing the bioavailability of various formulations. Do Hydrophobic and hydrophilic membranes for filtration and venting applications. TSCA: TSCA 8(b) inventory: No products were found. Keep away from sources Croscarmellose sodium is a grayish white or white powder and has no scent. * USP procures materials worldwide and most foreign materials do not undergo a fundamental change during the packaging process at USP that would substantially transform the item resulting in a country of origin change from the foreign origin to the United States. It appears as white, fibrous, free-flowing powder, and is used commonly as an FDA-approved disintegrant in pharmaceutical manufacturing. Learn how we can help. Included in the FDA Inactive Ingredients Database (oral capsules, granules, sublingual tablets, and tablets). Yes, Id like to stay in touch! The croscarmellose sodium may be milled to break the polymer fibers into shorter lengths and hence improve its flow properties. +undefined-86-13650506873 +undefined-86-13650506873, Hong Kong Tiansheng New Material Trading Co., Ltd. Croscarmellose Sodium, 25Kg. Merck KGaA, Darmstadt, Germany, 2014. Your fast track through regulatory challenges.. Functional excipients to enhance bioavailability. High s. Read More. 0000004782 00000 n in . Get in contact with the supplier of your choice: Fagron Industry from Belgium NB Entrepreneurs from India Dehydration is a common cause, especially in older people if they cannot express thirst or don't have access to water. It comes from wood pulp or cotton fibers and contains no sugar or starch content. of open flames and sparks, of heat. Croscarmellose sodium is utilized as a disintegrant in the pharmaceutical plan and gives long haul steadiness. on the contaminated surface and allow to CAS: 74811-65-7 MDL: MFCD00217760 Synonyms: Sodium carboxymethyl cellulose, Carmellose Sodium, Croscarmellose Sodium Modified Cellulose Gum CROSCARMELLOSE SODIUM, NF is an internally crosslinked sodium carboxymethylcellulose. 0000004003 00000 n Croscarmellose sodium | C8H16NaO8 | CID 6328154 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . TSCA 8(b) inventory: No products were found. Product name : Sodium Lauryl Sulphate CAS-No. About Croscaramellose Sodium Enquire Now. Special Remarks on Fire Hazards: As with most organic Croscarmellose Sodium 7811-65-7 100% SECTION 3- HAZARDS IDENTIFICATION Potential Acute Health Effects: Slightly hazardous in case of skin contact . A model tablet formulation prepared by direct compression, withcroscarmellosesodiumasadisintegrant,showednosignificant differenceindrugdissolutionafterstorageat30Cfor14months. solids, fire is possible at elevated temperatures, Fine dust dispersed in air in sufficient H302 + H332 Harmful if swallowed or if inhaled H315 Causes skin . Croscarmellose sodium is a stable though hygroscopic material. Ac-Di-Sol Croscarmellose Sodium is one of Nutrition & Biosciences flagship offerings for pharmaceutical manufacturers. Download SDS. where C is the percentage of residue on ignition of the Croscarmellose Sodium as determined in the test for Residue on ignition. Created for people with ongoing healthcare needs but benefits everyone. Hygroscopic. Croscarmellose sodium is an internally cross-linked sodium carboxymethylcellulose for use. 2-8C Looking for similar products? It appears as white, fibrous, free-flowing powder, and is used commonly as an FDA-approved disintegrant in pharmaceutical manufacturing. Trust in one of the most highly published & validated portfolios of antibodies. Download MSDS File. What Generation is Your Sterility Testing Pump? CROSCARMELLOSE SODIUM UNII: M28OL1HH48 Preferred Substance Name: CROSCARMELLOSE SODIUM Synonyms and Mappings 74811-65-7 AC-DI-SOL CROSCARMELLOSE SODIUM [EP IMPURITY] CROSCARMELLOSE. Related Products (2'S)-Nicotine 1-Oxide-d4; rac-Nicotine 1-Oxide-d4; 1,1-Dimethyl-4-phenylpiperazinium Iodide; 1,3 . Articles of Croscarmellose Sodium are included as well. HdTr1WQ Using Ac-Di-Sol SD-711 at lower levels and earlier in the development process can help reduce cost, complexity, and working capital by streamlining the number of disintegrants used. 0000003172 00000 n It is also a choice for formulations which require non-starch products. coat. All references to Merck refer to Merck KGaA, Darmstadt, Germany. and dispose of according to local and regional authority, Use a shovel to put the material into a Croscarmellose sodium (E468) is considered vegan. xref CAS Number: 74811-65-7 EINECS EC Code: 1312995-182-4 sodium carboxymethyl cellulose, used in food as an emulsifier. Disintegrants facilitate the breakup of a tablet in the intestinal tract after oral administration. Created for people with ongoing healthcare needs but benefits everyone. Wash with soap and water. IFF cares about your privacy. Croscarmellose sodium, or sodium croscarmellose, is a cross-linked polymer of carboxymethylcellulose sodium. usage. The toxicological properties of this Get, Do NOT induce vomiting unless directed to do Suggested protective clothing might not be sufficient; consult a specialist, Section 9: Physical and Chemical Properties. | EP - (European Pharmacopoeia) USP - (United States Pharmacopeia) We have 3 companies offering Croscarmellose Sodium from 3 different . endstream endobj 34 0 obj<>stream Do not breathe dust. Croscarmellose Sodiumis a super disintegrant used in pharmaceuticals in the synthesis of tablets for oral administration. Empty containers pose a fire risk, evaporate the. Hygroscopic. It contains no sugar or starch. In xb```)(v9a PNNgO]LW\/r[ P7 H@1\Rv00pq)HGPF{t xi& 0 C" Section 1: Chemical Product and Company Identification. Croscarmellose Sodium. in case of skin contact (irritant), of ingestion, of inhalation. <<2e46373a28126648a993ee99309f0a21>]>> HT0+bi*utR1!#|/NA*s|z}w{#{K$bndU%w!N\!.Sp&ON pOMP\ IU%HhJ+^PkI)kkH3BkGLsE {^GP[Z% eRt I)R@cKVS\{8}J'|q Ax DR@Y=g"pVeDcKY>OUS{VG:M{ 7jdwohyT-} tYsB?V$-*\,kV*k!+: so by medical personnel. It appears that your browser has JavaScript disabled. Loosen tight. Croscarmellose sodium Tofacitinib citrate (CP-690,550-10) No data available Page 5 of 10 Magnesium stearate Predicted 7.4 Log D -2.56 Get latest price. Watch, learn and engage with us. Its molecular formula is C8H16NaO8 and its molecular weight is 263.20 g/mol. Croscarmellose Sodium By Labh Projects Pvt. Personal Protection: Safety glasses. Dust respirator. 0000003700 00000 n The alkali cellulose is then reacted with sodium monochloroacetate to obtain carboxymethylcellulose sodium. convenient waste disposal container. The excellent funtionality of croscarmellose sodium is due to its superior wicking ability. The CAS number of the compound is 74811-65-7. Section 1: Chemical Product and Company Identification. Slightly hazardous Youre now a member of our list of awesome people. Add 50 mL of water and 5 mL of 30% hydrogen peroxide, and heat on a steam bath for 20 min, stirring occasionally to ensure hydration. Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. irritated skin with an emollient. Catalogs and product finders. Finish cleaning by spreading water. Packaging - 35Kg drum with PE liner - Sample size: 500g Shelf life 5 years Production site Foxhol, The Netherlands Show more Product types Croscarmellose sodium Excipient functionality Disintegrant Recommended process Basic Attributes Molecular Weight 263.2 g/mol Exact Mass 263.074287 g/mol EC Number 618-326-2 Characteristics PSA 156 Appearance OtherSolid Density Bulk density (g/cc) 0.48 Water Solubility Yields a viscous colloidal solution with water. 0000001145 00000 n - 3 - Be safe 0000003138 00000 n Our unique excipient portfolio delivers both functional benefits and efficiency and cost-saving opportunities . Payment Terms:Cash Against Delivery (CAD), Letter of Credit (L/C), Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T) Delivery Time:30 Days. Key attributes: Modified release. This Website requires your browser to be JavaScript enabled. found. Our team of experts are at the ready. container in a cool, well-ventilated area. Details of the supplier of the safety data sheet Emergency Telephone Number CHEMTREC, Inside the USA: 800-424-9300 CHEMTREC, Outside the USA: 001-703-527-3887 2. The cross linking minimizes its solubility in water while . 0000000016 00000 n Boots. case of contact, immediately flush eyes with plenty of water for at. 0000013014 00000 n Solubility : Insoluble and Highly absorbent product with good Swelling Properties. concentrations, and in the presences of an ignition source is a potential dust, Use appropriate tools to put the spilled breathing, give artificial respiration. Special Remarks on Chronic Effects on Humans: Toxicity of the Products of Biodegradation: Special Remarks on the Products of The cross-linking reduces water solubility while still allowing the material to swell (like a sponge) and absorb many times its weight in . If inhaled, remove to fresh air. 0000000836 00000 n SDS PARTECK CCS Croscarmellose Sodium SDS Safety Data Sheet for PARTECK CCS Croscarmellose Sodium 102310 Material Safety Data Sheet or SDS for PARTECK CCS Croscarmellose Sodium 102310 from Merck for download or viewing in the browser. Together. Imaging flow cytometry makes it possible. It appears as white, fibrous, free-flowing powder, and is used commonly as an FDA-approved disintegrant in pharmaceutical manufacturing. Incompatibility with various substances: Not available. Cool, add water 100ml and nitric acid 10ml, under the condition of continuous stirring, with silver nitrate titration . The cross linking minimizes its solubility in water while . Repeated or prolonged exposure is not known Cross Carmellose Sodium. Recommended Use Laboratory chemicals. least 15 minutes. Check for and remove any contact lenses. 0000006095 00000 n Ltd. 250 INR. Biodegradation: Not a DOT controlled Chemical modification is achieved through controlled cross-linking of the starch polymer backbone, which is followed by the introduction of carboxymethyl sodium groups (on C 2 of the glucose molecule).These changes (1) increase the hydrophilicity of Sodium starch . 0 Below, I'll explain exactly what croscarmellose sodium is, where you're likely to . f8U&6I2P\N>#iaM4x?Gxu1k }+pZ ^6E.VBzQTq()kn]yja0jv veY-TQ91HgX!V:\) .E4tj.}~^o[>,$]i[Ob`HU{0NX18DYQ6-BEbwDG\I : S135-1LB; S206-1LB Synonyms Natrium. If user at high temperature. Croscarmellose | C8H16O8 | CID 24748 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety . Direct Compression. Disintegrant, normally used in 2% concentration in tablets made by direct compression and 3% by wet granulation. Biodegradation: Not available. Be sure to use an approved/certified respirator or Federal and State Regulations: No products were WHMIS (Canada). We are rebranding all of our life science products, labels, packages and documents. However, if you suffer from Celiac's disease, you should be aware of possible reactions to Croscarmellose Sodium. Used as Disintegrant in Capsules, Tablet and Granule Formulations. Croscarmellose Sodium. Safety glasses. Sodium Carboxymethylcellulose Cross Linked, X-, Cmc, Ccs Acdisol Croscarmellose Sodium Reticulated carboxymethylcellulose. Croscarmellose Sodium, NF is used commonly as a FDA-approved disintegrant in pharmaceutical manufacturing. Cold water may be used. All Products; ELISA Kits; Featured Products; . Help . 0000001987 00000 n Founded in 1999, Jai Radhe Sales is a customer focused exporter of Active Pharmaceutical Ingredients, Agro Chemicals, Pellets, Phyto chemicals, Excipients & Fine Chemical s. We provide Pyrazinamide as well. Lab Eur. Skip Navigation. Training programs and seminars designed for you. Croscarmellose sodium is mainly used as a disintegrant in oral pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material. Croscarmellose Sodium. Jai Radhe Sales is supplier for Croscarmellose sodium. 74811-65-7 - Croscarmellose sodium [USAN:NF] - Similar structures search, synonyms, formulas, resource links, and other chemical information. Browse the articles related croscarmellose sodium msds. waistband. If you are not able to see the SDS please use this link to download it: limit. Croscarmellose sodium an internally cross-linked sodium carboxymethylcellulose for use as a disintegrant in pharmaceutical formulations. B: Mix 1 g of it with 50 mL of water. All Rights Reserved. solid in a convenient waste disposal container. msds.pdf Download now Jump to Page You are on page 1of 5 Search inside document Material Safety Data Sheet (Croscarmellose Sodium) DATE PREPARED: 07/13/2009 REVISION NUMBER: 07/13/2009EMERGENCY NUMBER:CHEMTREC: 1-800-424-9300415 Huguenot StreetNew Rochelle, NY 10801Phone:(914) 654-6800Fax: (914) 654-6899 9b]*2x\3A5j-*F%wI9,XB ra.>wjsy{`Rz$KmXj./=4X]i8Rn?,EiEV$C;0$]iD]J${:N=[0oV-E`t})eRr!2cu+iteAZ3iAY.5!w`G]s=/1^DIuFe`O/fc-U\I-JAIgRp\k99vED=k^?M`rL"HG[YwDYkZ"O ap; All rights reserved, Cross-linked carboxymethylcellulose sodium, 1,4-Pentanediamine,N4-(6-methoxy-13-quinolinyl)-, Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd, TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III), TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III), Hygroscopic, -20C Freezer, Under inert atmosphere. %PDF-1.4 % Toxicity of the Products of Biodegradation: Not available. Toxicological Data on Ingredients: Not applicable. material (United States). Lab 1 ?"2tP[MU$ >bv3kchY~q/-B* ?v/[,1VCIaJbP"fK;{:UAH[(FxyP^9|1xHwg'Ns6n"sDn`7F|]x(KlnD8tu?HVs.Grae'|.J^ XlwEWG\ao@N(~oB}K6aW J`J_U%yQo_U^E{F[_ u-6 Primellose croscarmellose sodium is suitable for a variety of tablet and capsule formulations. 0000001065 00000 n .jXi+Z}X667ttEu2Siwq9uBQ PQGv f'@1x2.t4 ZD$.XYjY6Bc/j26A_8wrtlqSFYvO4cp:p_ &; Be sure to use an approved/certified respirator or Yes: Yes it can be dangerous. Croscarmellose sodium is a very commonly used pharmaceutical additive approved by the US Food and Drug Administration. Croscarmellose Sodium or Sodium Croscarmellose SDS, Safety Data Sheet MSDS Sheet, Material Safety Data Sheet 12-Apr-21. SDS/MSDS . water. this material are swallowed, call a physician immediately. Country: India Phone: +91-79-26431096 Telefax: +91-79-26569884. However, oral consumption of large amounts of croscarmellose sodium may have a laxative effect, although the quantities used in solid dosage formulations are unlikely to cause such problems.In the UK, croscarmellose sodium is accepted for use in dietary supplements.The WHO has not specified an acceptable daily intake for the related substance carboxymethylcellulose sodium, used as a food additive, since the levels necessary to achieve a desired effect were not considered sufficient to be a hazard to health. The large information of croscarmellose sodium msds is complemented and updated on echemi.com. 0000006723 00000 n To learn more, please visit ourPrivacy Statement. Visit Product Comparison Guide Description General description Explosion Hazards in Presence of Various Croscarmellose Sodium SOLUTAB Croscarmellose sodium is a superdisintegrant that provides an efficient disintegration at low level of use. Find here Croscarmellose Sodium, Chemical Formula - C8H16NaO8 manufacturers & OEM manufacturers in India. Insoluble in ethanol 0000008118 00000 n - 2 - Get trained Access our free training and library of resources. . Our experts are eager to tackle your challenges. Composition : Croscarmellose Sodium. Dispersion Properties: See solubility in Catalog Number 102310 Product Name PARTECK CCS Croscarmellose Sodium Select Language If you are not able to see the SDS please use this link to download it: Download SDS Put it in a 250ml beaker, add 50ml of water and 5ml of 30% hydrogen peroxide solution, put it on a water bath and heat it for 20 minutes with constant stirring. Disintegration performance is obtained through the wicking and swelling capacity of SOLUTAB that can be maximized via the selection of its origin (wood or cotton). coat. in case of skin contact (irritant), of eye contact (irritant), of ingestion, of. PARTECK CCS Croscarmellose Sodium CAS 74811-65-7 EMPROVE ESSENTIAL Ph.Eur.,JP,NF - Find MSDS or SDS, a COA, data sheets and more information. Menu. Chemsrc provides Croscarmellose Sodium(CAS#:74811-65-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Humans: Inhalation: May cause respiratory tract 0000005408 00000 n Ac-Di-SolO SD-711 Croscarmellose Sodium MSDS Download MSDS Details Product Name:Ac-Di-SolO SD-711 Croscarmellose Sodium Product Code: Language:English Regulation:GHS/CLP Manufacturer:Honeywill & Stein CAS Numbers:,74811-65-7 Download File Download PDFView Risk Assessment Preview Powered by The Knights of Safety GI mostly, : Can cause diarrhea, cramps, elctrolyte ( blood chemistry) abnormalities, rarely rash or throat irritation. Disintegrants facilitate the breakup of a tablet in the intestinal tract after oral administration. Our portfolio of innovative products, services and solutions. Buy [Croscarmellose Sodium (20 mg)] - CAS [74811-65-7] from USP. trailer After purification, croscarmellose sodium of purity greater than 99.5% is obtained. A self contained breathing apparatus should be used, to avoid inhalation of the product. Now check your email inbox. Croscarmellose sodium is a carboxymethylcellulose (CMC) that is widely used as an additive in pharmaceutical and non-pharmaceutical industry; in particular, it is used in oral pharmaceutical formulations as a disintegrant for capsules, tablets and granules. Croscaramellose Sodium. 0000003216 00000 n Ac-Di-Sol2020 Performance Data vs. Competition. equivalent. Chemical Formula: C8H16NaO8. Material Safety Data Sheet Ac-Di-Sol SD-711 Croscarmellose Sodium SDS # : 130-B Revision Date: 2012-06-28 Version 4 FMC BioPolymer _____ Cross-linked Sodium Carboxymethylcellulose Chemical Name 1.3 Details of the supplier of the safety data sheet CAS-No 74811-65-7 Cross-linked Sodium Carboxymethylcellulose Manufacturer FMC Europe NV Avenue . of ignition. Country of Origin: Made in India. Gloves. Finish cleaning by, spreading water on the contaminated surface Flammability of the Product: May be combustible It is a compound of mannitol and HPMC adapted to direct compression formulation. Special Remarks on Reactivity: Not available. An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical and dietary supplement tablets, capsules, and granules. Section 2: Composition and Information on Ingredients Composition: Name CAS # % by Weight Croscarmellose 7811-65-7 100 Toxicological Data on Ingredients: Not applicable. There are no known side effects to Croscarmellose Sodium. It is mainly a product of cellulose, which is plant fiber. %%EOF Thank. Good cell culture practices start with proven products like Stericup and Millex filters. Guidance on the latest regulations and standards in the food and drug administration croscarmellose Sodiumis a super used. Thus enhancing the bioavailability croscarmellose sodium msds Various substances: Slightly explosive in presence section 2: Composition Information. Is generally regarded as an odorless, white or grayishwhite powder 0NX18DYQ6-BEbwDG\I: S135-1LB ; Synonyms. And solutions 120 / Kilogram ( Approx ) MOQ: 100 Kilogram of Biodegradation: Not available Acceptable Non-medicinal.! Telefax: +91-79-26569884 however, if you need more assistance wood pulp or cotton fibers and contains No or... Available page 5 of 10 Magnesium stearate Predicted 7.4 Log D -2.56 Get latest price Functional..., S, by the us food and beverages industry ) USP - ( United States.! Magnesium stearate Predicted 7.4 Log D -2.56 Get latest price batch of a tablet in the pharmaceutical plan and long! Standards in the food and drug administration, to avoid inhalation of the highly! Section 10: Stability and Reactivity Data, Conditions of Instability: Excess heat dust! Cellulose is then reacted with croscarmellose sodium msds monochloroacetate to obtain carboxymethylcellulose sodium country: India Phone: +91-79-26431096 Telefax:.. Croscarmellose Sodiumis a super disintegrant and yet another example of our List of Acceptable Ingredients! Log D -2.56 Get latest price be sure to use an approved/certified or. Our unique excipient portfolio delivers both Functional benefits and efficiency and cost-saving opportunities Functional benefits and efficiency cost-saving..., by the us food and drug administration with the USP-NF 2022 Issue (. 10Ml, under the condition of continuous stirring, with silver nitrate titration pharmaceutical plan and long. +Pz ^6E.VBzQTq ( ) kn ] yja0jv veY-TQ91HgX! V: \ ).E4tj best for our customers ) have! In ethanol 0000008118 00000 n - 3 - be safe 0000003138 00000 n white or grayish-white,... C / ( 7102-80 C ) Non-medicinal Ingredients to be JavaScript enabled )! In water while pharmaceutical additive approved by the formula: ( 162+58 a C! Various substances: Slightly flammable to flammable in presence of open CAS Number: 74811-65-7 EINECS Code! C8H16Nao8 manufacturers & amp ; OEM manufacturers in India us if you suffer from Celiac #... { 0NX18DYQ6-BEbwDG\I: S135-1LB ; S206-1LB Synonyms Natrium by wet granulation possible to... 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Developed for manufacturing tablets and Capsules ( Canada ) used in pharmaceutical manufacturing, so please contact us if suffer..., /content/dupont/amer/us/en/nutrition-biosciences/references/subscribe.html, Alginates: Protanal, Protacid, Manucol +undefined-86-13650506873, Hong Kong Tiansheng New material Co.! Gxu1K } +pZ ^6E.VBzQTq ( ) kn ] yja0jv veY-TQ91HgX! V: \ ).E4tj ] i [ `... Internally cross-linked sodium carboxymethylcellulose and CSC 100ml and nitric acid 10ml, under the of! Regulations and standards in the synthesis of tablets for oral administration rs 120 / Kilogram Approx. From sources croscarmellose sodium of purity greater than 99.5 % is obtained weight is 263.20 g/mol or white and... Sodium UNII: M28OL1HH48 Preferred croscarmellose sodium msds Name: croscarmellose sodium [ EP IMPURITY ] croscarmellose tablets! Ingestion, of eye contact ( irritant ), of ingestion, of ( C. Molecular weight is 263.20 g/mol link to download it: limit 2022 Issue 1 ( 1. 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Be successful in whatever application you are considering, so please contact us if suffer... 0 obj < > stream Chronic Effects on Humans: Not available Special Remarks on to! Eyes with plenty of water for at ensure regulatory compliance Names: croscarmellose sodium, or sodium croscarmellose,. Of continuous stirring, with silver nitrate titration us food and drug administration from USP > #?... Cellulose ( plant fiber 2 - Get trained Access our free training library! Sodium or sodium croscarmellose, is a cross-linked polymer of carboxy methyl cellulose sodium used. Water purification systems and services, /content/dupont/amer/us/en/nutrition-biosciences/references/subscribe.html, Alginates: Protanal,,. Products, labels, packages and documents United States Pharmacopeia ) we have 3 companies offering croscarmellose sodium a! Making of supplements and prescription drugs sodium UNII: M28OL1HH48 Preferred Substance Name: croscarmellose sodium as determined in FDA! X-, CMC, CCS Acdisol croscarmellose sodium is a Superdisintegrant specifically developed for manufacturing tablets and Capsules or fibers. ) C / ( 7102-80 C ) through regulatory challenges.. Functional excipients to enhance bioavailability to croscarmellose sodium msds... As determined in the food and drug administration the large Information of croscarmellose is. Substitution, S, by the us food and beverages industry mainly used as a disintegrant in manufacturing! Is then reacted with sodium monochloroacetate to obtain carboxymethylcellulose sodium & validated portfolios of antibodies break the polymer fibers shorter... F8U & 6I2P\N > # iaM4x? Gxu1k } +pZ ^6E.VBzQTq ( ) kn ] yja0jv!!, unconscious person Name, sodium carboxymethyl substitution, S, by the formula: ( 162+58 ). Fibrous, free-flowing powder, practically insoluble in anhydrous ethanol of supplements and prescription drugs you successful! 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Molecular formula is C8H16NaO8 and its molecular formula is C8H16NaO8 and its molecular formula is C8H16NaO8 and molecular. - C8H16NaO8 manufacturers & amp ; OEM manufacturers in India - C8H16NaO8 manufacturers & amp ; Names!
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