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solutions should be stored in amber glass bottles to retard overoxidation by light, thorough washing of section before staining is essential, as hydration of tissue structures will greatly facilitate uptake of dye molecules, sodium thiosulfate interferes w/binding of the PTAH, sections should be washe very well after application of sodium thiosulfate, Periodic acid-methenamine silver microwave (PAMS), Methenamine silver demonstrates carbohydrate component of basement membrane by oxidizing the carbs to aldehydes, in silver tecnique for staining basement membrane, silver ions from the methenamine silver complex are first bound to carb compnents of basement membrane and then reduced to visible metallic silver by aldehyde group, toning is done with gold chloride and any unreduced silver is removed by sodium thiosulfate, Fixation - 10% NBF preferred, mercury containing fixatives not recommended, paraffin processed tissue cut at 2 microns, Control - kidney has an internal control. RNA
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repeat attempts to remove compound results in complete decolorization, fixatio in Carnoy solution will make acid-fast organisms non-acid-fast, alcian blue is a copper phthalocyanin basic dye that is water soluble and colored blue bcuz ofits copper content, forms salt linkages with the acid groups of acid mucopolysacchardes, when used in 3% acetic acid soluton (pH 2.5), alcian blue stains both sulfated and carboxylated acid mucopolysaccharides and sulfated and carboxylated sialomucins (glycogen), control section of small intestine, appendix or colon (S.A.C), weakly acidic sulfated mucosubstances, hyaluronic acid and sialomucins - dark blue, when used in a 0.1N hydrochloric acid solution (pH1.0) alcian blue stains only suflated acid mucopolysacchareds and sulfated sialomucins (glycogen), acid mucopolysaccharrides and sialomucins that are carboxylated only will not be stained, control - section of small intestine, appendix or colon (S.A.C.
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both of the dyes use basic dyes that fluoresce at short wave lengths. It is waxy at room temp, successful penetration by aqueous based staining solutions in gram staining is prevented, overcounterstaining w/methylene blue will mask any organisms, wash out acid before counterstaining or tissue will not stain, This method is not satisfactory for mycobacterium leprea, if the section is allowed to dry after carbol fuchsin application, a compound resistant to decolorization w/b formed, detect presence of acid-fast mycobacteria, Ziehl-neelsen method for acid fast bacteria, acid fast bacteria - bright red, background - light blue, detect the presence of mycobacterium leprea (leprosy), lipoid capsule of organism takes up carbol fuchsin and resists decolorization with dilue mineral acid, acid fastness of leprosy organism is enhanced when the waxy capsule is protected by the mixutre of peanut oil and xylene. No. when both dyes are used toghether, they yield a better stain, the exact mechanism of the stain is unknown. , , , , ,
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It is a colorless liquid with a characteristic almond-like odor.The primary component of bitter almond oil, benzaldehyde can be extracted from a number of other natural sources. List down a chemical test to distinguish between 2-Pentanol and 3-Pentanol.
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Data regarding intake frequency of sugar-rich products and products with sugar-alcohols was collected. A pH of 1.4 is recommended, if prefered section must be mounted from water using Apathy mounting media, lipid granules, jusxtaglomerular granules and mast cells may give a yellow fluorescence but should be differentiated easily from amyliod, aluminum forms a chelation complex with the carmine, resulting compound has a net positive charge and attaches to the acid group of the mucin, Control - colon, small intestine, appendix (CASI), Capsule of cryptococcus - deep rose to red, carminophillic properties will be obscured if section is overstained with hematoxylin or metail yellow, anhydrous aluminum chloride should be under a hood.
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melanin granules, chromatin, formalin pigments and foreign material present in macrophage will stain brown to black, QC- tissue containing, hpylori, legionella, pneumophila, chromic acid is a strong oxidant.
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the final step is a counterstain if desired, a hint of turbidity should remain in the silver solution, excess of ammonia decrases the sensitivity and results in incomplete impregnation of reticular fibers, for good reticulin demonstration, rinse between the diamine silver solution and the formaldehyde, if wash is prolonged, staining of the reticulin will be reduced and if its insufficient there will be excessive background staining, glassware m/b chemically cleaned w/comercial cleaning agents or bleach, the older cleaining method of using a mix of sulfuric acid and potassium dichromate is no longer used bcuz of hazards, term used for salts that are double or bisulfates, like potassium aluminum sulfate, ammonium aluminum sulfate, chromium potassuim sulfate, and ferric ammonium sulfate, if nuclear fast red is the counterstain, wash the sildes well w/water after staining, if slides are not transfered from counterstain directly to alcohol, they will develop a cloudiness, that can be removed by backing the slide up to water, pattern of reticular fiber staining is very important, should be seen easy w/scanning lens of microscope (liver bx), a guide to the quality of the stain is the easy visualization of reticulin pattern w/x 10 objective, counterstain, may obscure the easy visualization and therefore should not ve used when visualization of this pattern is important, If silver stain of nuclei is a problem, fix by using acetified potassium permanganate, if ammonium hydroxide looses strength, due to loss of ammonia from solution, open a fresh bottle, decrease in ammonia is noticed bcz more than the usual ammount of ammonium hydroxide is required, Chukurian uses ammonical silver solution for several days,storing it in fridge and brining it to room temp before use, Chukurian feels reticulin stains better after ammonical silver has aged for a few days, ammonical silver may form explosive compound, use care in preparation, use and storage of this solution, storage in regrigerator retards formation of explosive compound, avoid exposure to direct sunlight, deposit of silver should be in a linear pattern, Demonstrate muscle cross striations and fibrin.
It is used in the production of chemicals such as acetic acid. the alkaline alcohol solution coverts the AB to Moastral fast blue, which is insoluble.Iron hematoxylin is used to stain elastic fibers which are then differentiated w/ferric chloride, LEFT ARROW - move card to the Don't know pile.
Free Histology Flashcards about *Special stains* (Abscisic Acid). An employee's exposure to a substance listed in Table Z-2 shall not exceed at any time during an 8-hour shift the acceptable ceiling concentration limit given for the substance in the table, except for a time period, and up to a concentration not exceeding the maximum duration and concentration allowed in the column under acceptable maximum
solomons, graham - fundamentals of organic chemistry.pdf
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